Gardasil Researcher Speaks Out – CBS News, lead works.#Lead #works


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Gardasil Researcher Speaks Out

Lead works

Dr. Diane Harper says young girls and their parents should receive more complete warnings before receiving the vaccine to prevent cervical cancer. Dr. Harper helped design and carry out the Phase II and Phase III safety and effectiveness studies to get Gardasil approved, and authored many of the published, scholarly papers about it. She has been a paid speaker and consultant to Merck. It’s highly unusual for a researcher to publicly criticize a medicine or vaccine she helped get approved.

Dr. Harper joins a number of consumer watchdogs, vaccine safety advocates, and parents who question the vaccine’s risk-versus-benefit profile. She says data available for Gardasil shows that it lasts five years; there is no data showing that it remains effective beyond five years.

This raises questions about the CDC’s recommendation that the series of shots be given to girls as young as 11-years old. “If we vaccinate 11 year olds and the protection doesn’t last. we’ve put them at harm from side effects, small but real, for no benefit,” says Dr. Harper. “The benefit to public health is nothing, there is no reduction in cervical cancers, they are just postponed, unless the protection lasts for at least 15 years, and over 70% of all sexually active females of all ages are vaccinated.” She also says that enough serious side effects have been reported after Gardasil use that the vaccine could prove riskier than the cervical cancer it purports to prevent. Cervical cancer is usually entirely curable when detected early through normal Pap screenings.

Dr. Scott Ratner and his wife, who’s also a physician, expressed similar concerns as Dr. Harper in an interview with CBS News last year. One of their teenage daughters became severely ill after her first dose of Gardasil. Dr. Ratner says she’d have been better off getting cervical cancer than the vaccination. “My daughter went from a varsity lacrosse player at Choate to a chronically ill, steroid-dependent patient with autoimmune myofasciitis. I’ve had to ask myself why I let my eldest of three daughters get an unproven vaccine against a few strains of a nonlethal virus that can be dealt with in more effective ways.”

Merck and the Centers for Disease Control and Prevention maintain Gardasil is safe and effective, and that adequate warnings are provided, cautioning about soreness at the injection site and risk of fainting after vaccination. A new study in the Journal of the American Medical Association found while the overall risk of side effects appears to be comparable to other vaccines, Gardasil has a higher incidence of blood clots reported. Merck says it continues to have confidence in Gardasil’s safety profile. Merck also says it’s looking into cases of ALS, commonly known as Lou Gehrig’s Disease, reported after vaccination. ALS is a progressive neurodegenerative disease that attacks motor neurons in the brain and spinal cord. Merck and the CDC say there is currently no evidence that Gardasil caused ALS in the cases reported. Merck is also monitoring the number of deaths reported after Gardasil: at least 32. Merck and CDC says it’s unclear whether the deaths were related to the vaccine, and that just because patients died after the shots doesn’t mean the shots were necessarily to blame.

According to Dr. Harper, assessing the true adverse event risk of Gardasil, and comparing it to the risk of cervical cancer can be tricky and complex. “The number of women who die from cervical cancer in the US every year is small but real. It is small because of the success of the Pap screening program.”

“The risks of serious adverse events including death reported after Gardasil use in (the JAMA article by CDC’s Dr. Barbara Slade) were 3.4/100,000 doses distributed. The rate of serious adverse events on par with the death rate of cervical cancer. Gardasil has been associated with at least as many serious adverse events as there are deaths from cervical cancer developing each year. Indeed, the risks of vaccination are underreported in Slade’s article, as they are based on a denominator of doses distributed from Merck’s warehouse. Up to a third of those doses may be in refrigerators waiting to be dispensed as the autumn onslaught of vaccine messages is sent home to parents the first day of school. Should the denominator in Dr. Slade’s work be adjusted to account for this, and then divided by three for the number of women who would receive all three doses, the incidence rate of serious adverse events increases up to five fold. How does a parent value that information,” said Harper.

Dr. Harper agrees with Merck and the CDC that Gardasil is safe for most girls and women. But she says the side effects reported so far call for more complete disclosure to patients. She says they should be told that protection from the vaccination might not last long enough to provide a cancer protection benefit, and that its risks – “small but real” – could occur more often than the cervical cancer itself would.

“Parents and women must know that deaths occurred. Not all deaths that have been reported were represented in Dr. Slade’s work, one-third of the death reports were unavailable to the CDC, leaving the parents of the deceased teenagers in despair that the CDC is ignoring the very rare but real occurrences that need not have happened if parents were given information stating that there are real, but small risks of death surrounding the administration of Gardasil.”

She also worries that Merck’s aggressive marketing of the vaccine may have given women a false sense of security. “The future expectations women hold because they have received free doses of Gardasil purchased by philanthropic foundations, by public health agencies or covered by insurance is the true threat to cervical cancer in the future. Should women stop Pap screening after vaccination, the cervical cancer rate will actually increase per year. Should women believe this is preventive for all cancers – something never stated, but often inferred by many in the population– a reduction in all health care will compound our current health crisis. Should Gardasil not be effective for more than 15 years, the most costly public health experiment in cancer control will have failed miserably.”

CDC continues to recommend Gardasil for girls and young women. The agency says the vaccine’s benefits outweigh its risks and that it is an important tool in fighting a serious cancer.

Dr. Harper says the risk-benefit analysis for Gardasil in other countries may shape up differently than what she believes is true in the US. “Of course, in developing countries where there is no safety Pap screening for women repeatedly over their lifetimes, the risks of serious adverse events may be acceptable as the incidence rate of cervical cancer is five to 12 times higher than in the US, dwarfing the risk of death reported after Gardasil.”


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Sign Up for Refinance Leads, Mortgage Refinance Lead Offers #refinance #leads,mortgage #refinance


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Credit Repair Leads – Why not supplement your mortgage income with another revenue stream that helps people out by improving their credit.

Please note that LeadPlanet.com does not offer home refinance programs. LeadPlanet.com is not a bank, credit union, broker or mortgage lender. LeadPlanet.com is a website that provides information about home financing and services that connect consumers to approved lending professionals. We do not offer refinance mortgages directly or indirectly through representatives or agents.

1999-Present, LeadPlanet.com, Lead Planet Company
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AccuData Integrated Marketing, Integrated Marketing Data Solutions, lead generation technologies.#Lead #generation #technologies


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    Andersen Environmental is a full service consulting firm that is comprised of leading environmental professionals dedicated to providing effective solutions for our clients’ environmental needs. Andersen Environmental’s services include: asbestos testing, Phase I Environmental Assessments, Phase II soil and groundwater testing, soil remediation including soil vapor extraction, hazardous waste characterization and removal, and many other services as listed below. Andersen Environmental’s corporate headquarters are located in Los Angeles, California, with offices throughout the United States.

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    B2B Digital Marketing #lattice #lead #scoring


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    Let s get right to the point. B2B marketers today are not optimizing programs to reach and engage their best prospects.

    Sure, we talk about a buyer journey or about carefully mapping content. But at the end of the day, what are we doing? We are scoring leads high if they consume a lot of content and we are optimizing our program to increase lead scores and content consumption.

    Who does that mean we are really optimizing our marketing for? Serial content consumers. [Read more ]

    2015 seemed like a breakout year for account-based advertising, with a flurry of account-based advertising offerings hitting the market. Interest in account-based advertising is, no surprise, following the adoption of account-based marketing.

    According to a 2015 survey from Demand Metric and Demandbase, 45% of B2B marketers are testing or have adopted account-based marketing and more than 75% of those plan to increase their use of ABM in the next year. LUMA Partners even singled out Account Based Marketing as an area they expect to take off within MarTech this year.

    On the surface, if your marketing is already structured around specific accounts, using account-based targeting in your advertising programs seems like a natural next step. But how do these solutions actually target ads to specific companies? Or to put it a little bit differently, how do all of these companies most of us have never heard of know where we all work? [Read more ]

    A few weeks ago I was talking to Maureen Blandford about marketers, marketing technology, and the need for all of us to move faster.

    Our conversation turned to skill sets and the current digital and technology skills gap in marketing today. A thought I had in that conversation has been gnawing at me since: Today s marketers don t have the aptitude for marketing technology. [Read more ]

    As I came back from the B2B Marketing Innovation Summit, put on by Demandbase, I couldn t shake the feeling that we aren t doing enough. That I m not doing enough.

    Sure, marketing is changing faster today than it did yesterday. Blah blah blah. It doesn t matter how fast marketing is changing! The real question is how are you changing?

    Here are six areas that struck me. No, they aren t new. But they are places many B2B marketers, including myself, should be doing so much more. [Read more ]

    Sometimes the best advice and perspective doesn t come from the public figures we hear at conferences or see quoted in publications. It comes from the people who are hands on, doing the work in a wide range of situations.

    Toby is one of those guys. You probably don t know Toby, but maybe you should. He recently joined Business Insider as the Sales Director for the Southeast, after a number of years with CBSi, parent to B2B technology focused properties ZDNet and TechRepublic (among others). Like many of the people I work with at publishers, Toby works on more programs in a month than many of us work on in a year and that position gives him first hand insight into what is working, and what isn t, at scale. [Read more ]


    It is that time of year again. The time when predictions of the obvious abound and resolutions are quickly broken.

    I ll spare you my New Year s resolutions (well, most of them at least, read on). Instead, here are my five B2B marketing predictions for 2015. [Read more ]

    Your prospects spend the vast majority of their time doing everything except opening your emails, visiting your site or viewing your content.

    Despite the magic of marketing automation and the ability to collect information on every mouse movement on every page of our sites, we only get a tiny window into the lives of our prospects. And that tiny window can turn out to be very misleading. [Read more ]


    According to many in the digital advertising industry, at some point in the future digital marketing will be so targeted that consumers will want to see the ads. Advertising will tell us about the products we want to know about, give us a direct path to the content we need and provide access to discounts on products we want.

    How will marketers do this? Data, of course. Information marketers can use to determine what you are interested in. [Read more ]

    Digital marketers are getting hooked on reporting bigger numbers, but in the process your marketing may actually be making a smaller and smaller impact. [Read more ]


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    Lead Tracking Solutions – Financial Report #lead #tracking #solutions #annual #report, #lead


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    Lead Tracking Solutions is a privately-held lead tracking and lead management software company based in Costa Mesa, CA.

    Finding information on private companies can be painful. That’s why we created PrivCo – the ultimate private company financial research database – and why we have become the private company research provider and partner for hundreds of clients worldwide

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    One 26-Year-Old – s 5-Year Millionaire Lead Generation Plan #lead #generation #business


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    One 26-Year-Old s 5-Year Millionaire Lead Generation Plan

    Most people would tell you a 26-year-old doesn t have enough life experience to devise a lead generation plan that will make him a millionaire within 5 years. But Tim Heyl is no ordinary 26-year-old.

    Tim Heyl s First Year In Real Estate

    Tim Heyl had to borrow the fee to enroll in BOLD from his sister. That s a nice sister. Five years later, however, he has 13 members on his team, does $1.4 million in GCI, and had a total volume of $53 million!

    He started his real estate business fresh out of college. He enrolled in the KW MAPS Coaching BOLD program and learned about lead generation.

    “I remember making fewer than five calls the first hour we were given to call expireds,” he says. “I was intimidated. I’d never cold-called anyone before so I was loaded with limiting beliefs.

    By the end of the course, he was spending two hours a day on lead generation activities.

    He decided he was not going to work evenings or weekends. So he spent his weekday mornings making cold calls. During his first year, he used the phone to call on several sources, including expireds. and focused on three things:

    • Number of new contacts
    • Nurtures generated
    • Listing appointments set

    He says 30 contacts usually got him five nurtures and one appointment. At the end of the year he had only sold 20 houses, but

    What I didn t realize at the time was that I was building a pipeline that would explode a couple of years later.

    Lead Generation Years Two Through Four

    When chaos struck, Heyl had no idea how to deal with it. His team quit on him midway through the third year.

    Generating mass amounts of leads forced me to learn the qualities of true leadership at a much earlier age than I would’ve otherwise.

    That s when Heyl decided to start spending a lot of money on developing leadership skills. He started attracting new members of his team and built it up from scratch, focusing on leveraging the team using his leadership skills. This allowed him to free up his time for teaching instead of lead generation. He hired an inside sales agent (ISA) to generate leads for his sales team.

    He went on to build a team of ISAs and pays them a percentage of sales over and above their base pay.

    The Fifth Year of Lead Generation Leadership

    Tim Heyl keeps his eye on the future. The key to his success is leadership, teaching effective lead generation skills, and developing an ISA team that is motivated and productive.

    Our lead-generation room is separate to avoid distractions. We have standing desks, headsets, dual screens, a scoreboard that is updated daily, lively music being played and healthy snacks available to keep energy up. Our business is built in that room.

    Stay tuned for an update on Tim Heyl s sixth year in real estate. He and his team are sure to turn it up a notch and set more records. To learn how you too can build a successful real estate business with Keller Williams, contact us today to set up your confidential interview.


    Lead Management Overview and Resources #lead #managment #system


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    Lead Management

    What is Lead Management?

    Lead management is the process by which marketing acquires, evaluates, nurtures and hands off leads to the sales team. Sounds simple enough, right?

    Many companies have no standards in place for properly managing leads, so weeding out genuine buyers from those just poking around is difficult and time-intensive. Sales departments often receive weak leads, wasting more time and ultimately detracting from revenue. In fact, according to Gleanster Research, only 25% of leads in a given sales pipeline are legitimate prospects.

    Companies can significantly improve their sales pipeline by developing lead management strategies that incorporate lead nurturing, lead scoring and marketing automation.

    Ready to dive in to lead nurturing? Set some time aside to study the Definitive Guide to Lead Nurturing .

    Define Sales-Ready Leads

    Sales and marketing teams often have conflicting views of what constitutes a “qualified lead.” For instance, a marketer might consider any contact that responds to a marketing campaign to be a “lead,” but a sales representative might only care about leads that are ready to buy.

    Sales and marketing must work together to clearly define what they think a lead is. Consider the following criteria when evaluating your leads for sales-readiness:

    • Demographics: Geographic location, company size, etc.
    • Lead source: PPC search ad, social media and the offer they responded to.
    • Behavioral information: Web page visits, content downloads, event attendance, etc.

    Once lead criteria have been agreed upon, set up procedures and systems that enforce those criteria. Do leads that fit your criteria actually make a purchase? Ongoing measurement will allow you to use data to improve your definition of sales-ready leads over time.

    Nurture Sales Leads

    Once you have defined a sales-ready lead, it’s time to nurture your lead pool to generate as many sales-ready leads as possible.

    Lead nurturing is the process of delivering targeted, personalized resources and offers to your entire lead funnel to move prospects through the buying process. We have found that companies with excellent lead nurturing programs generate50% more sales-ready leads at 33% lower cost.

    How does a company nurture leads until they’re ready to buy?

    First, determine your prospects’ unique preferences. What topics interest them the most? What challenges are they wrestling with today? Do they respond better to emails, social media, webinars, or a mix of communication methods? Carefully evaluate which topics draw the most attention from individual prospects. An automated lead management tool will help track your customers’ likes and dislikes to coordinate the sophisticated communication strategy that lead nurturing requires.

    The most important characteristic of effective lead nurturing campaigns is to consistently deliver highly valuable, relevant (and branded) content.

    “Our business at Comvita is both B2B and B2C. A lot of solutions we looked at really pigeonholed us into what we could use it for, but Marketo had all the functionality and insight we were looking to achieve as well as the capabilities for both B2C and B2B. In only six months since we’ve had the lead nurture campaigns running, we are already seeing great results.” – Kylie Glover, Vice President of Marketing, Comvita [Source ]

    For a checklist of important things to know when it comes to lead nurturing, check out Marketo’s Lead Nurturing Cheat Sheet .

    Improve Lead Management with Lead Scoring

    Many businesses realize success by incorporating scoring methodologies into lead management, with the end goal of prioritizing leads for sales teams. According to a Customer Think survey, “Sixty-five percent of best-in-class companies define execute multi-step lead nurturing processes, and 59 percent of these same organizations (vs. an industry average of 25 percent) utilize lead scoring to progress leads over time.”

    Why is lead scoring so effective?By tracking your prospect’s behaviors and web activity, you determine not only their level of interest in your solution, but also your interest in them. This information will help your sales team spend their time on the leads that matter.

    Any effective lead scoring model should take into account all available data including demographics and behaviors. Use this data to define lead scoring thresholds that indicate whether a prospect is “qualified but still nurturing” or a true “sales-ready lead.”

    More and more companies choose to invest in scoring technology to reduce the time and hassle of manually sorting through leads. Lead scoring software automatically assess opportunities and passes them on to sales the instant they are deemed sales-ready.

    For a checklist of more than 250 B2B scoring rules, don’t miss The Big List of Lead Scoring Rules. And of course don’t forget the Definitive Guide to Lead Scoring .

    Utilize Lead Management Software

    According to an Aberdeen study. 71% of surveyed best-in-class companies said they utilized lead management technology. Automated lead management tools help companies monitor prospect behavior and engage in timely, individualized interactions more likely to generate revenue.

    One of the biggest reasons companies leverage the power of technology for managing leads is the sheer volume. Managing thousands or even millions of leads at a time is an overwhelming task for nearly any organization. The best solution is to software-driven automation rules capable of processing leads at lightning speed, while also introducing best practices to ensure win-ready opportunities are quickly identified and sent to sales.

    Automation also enhances the quality of customer data by removing duplicates or merging customer data from disparate sources. This important functionality provides sales with a clean, up-to-date list to work with in order to help you win more business, faster.

    We might be biased, but here’s some awesome lead management software to look into.

    Measure Your Lead Management Efforts

    Once you hammer down all the processes involved inacquiring and managing your leads, it’s time to evaluate your performance. Begin by assessing vital areas: the cost of acquiring or nurturing a lead, which marketing campaigns brought in the most prospects, and how long it took to convert leads to actual sales, among others. Tracking these types of metrics gives you insight into the efficiency and effectiveness of your lead management practices. It also provides perspective on how your marketing efforts are impacting your pipeline and your bottom line.

    By consistently monitoring the performance of your lead management activities, you will identify weaker activities and weed them out. You can also pinpoint those marketing activities which draw in the most business to create a culture of continuous optimization.

    “Marketo drives our entire revenue cycle management process, and takes lead management from generation to close. Without Marketo, we’d miss out on 30% of the opportunities that the company creates.” – Guy Goldstein, Online Marketing Manager, ARX [Source ]

    Conclusion: A Strategic Approach to Managing Leads

    Having a strategic method in place for lead management is vital to the success of any marketing effort, and for ensuring that sales have “qualified leads” (and lots of them!). When done correctly, lead management creates more-educated buyers, helps you better understand their needs and, ultimately, generates more revenue, faster.

    “Marketo is very user friendly—it really just makes sense if your job is to deliver either e-mail marketing or manage leads—it speaks the language that we marketers speak every day.” – Kristen Petersen, Director of Marketing Operations, F5 Networks [Source ]

    Additional Resources: